Use this URL to cite or link to this record in EThOS:
Title: Studies in biosynthesis of alkaloids
Author: Tiwari, Hanuman Prasad
Awarding Body: University of London
Current Institution: Imperial College London
Date of Award: 1965
Availability of Full Text:
Access from EThOS:
Access from Institution:
The biosynthesis of the Amaryllidaceae alkaloids is reviewed in the light of recent tracer studies. Feeding experiments with 14C and 3H labelled 0- _ methylnorbelladine have shown this phenol to be a precursor for norpluviine. Various degradations have been worked out to establish the labelling pattern in the alkaloid. On the basis of the results obtained, possible routes for the biosynthesis of norpluviine are discussed. Norpluviine has been shown to be an intermediate in the biosynthesis of galanthine. The existence of long range proton coupling in narwedine and Pummerer's ketone has been established by n.m.r. studies. The configuration of the allylic alcohols derived from Pummerer's ketone has been determined.
Supervisor: Barton, D.H.R. Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available