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Title: The synthesis of novel 6-azapyrimidine nucleoside analogues
Author: Jasamai, Malina
ISNI:       0000 0004 2749 0468
Awarding Body: Cardiff University
Current Institution: Cardiff University
Date of Award: 2006
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A series of novel acyclic oxonucleoside, 2',3'-dideoxy-4'-thio- and 4'-thio-L-nucleoside analogues have been prepared. An attempt to synthesise the acyclic thio moiety was unsuccessful. The novel analogues synthesised will be evaluated biologically at the Rega Institute in Leuven, Belgium as potential antiviral agents using a wide screen of viral assays including Human Immunodeficiency Virus type 1 and 2 (HIV 1 and HIV 2), Herpes simplex Virus type 1 and 2 (HSV 1 and HSV 2) and Varicella Zoster Virus (VZV).
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available