In this thesis, we investigate the problem of human layout estimation in unconstrained still images. This involves predicting the spatial configuration of body parts. We start our investigation with pictorial structure models and propose an efficient method of model fitting using skin regions. To detect the skin, we learn a colour model locally from the image by detecting the facial region. The resulting skin detections are also used for hand localisation. Our next contribution is a comprehensive dataset of 2D hand images. We collected this dataset from publicly available image sources, and annotated images with hand bounding boxes. The bounding boxes are not axis aligned, but are rather oriented with respect to the wrist. Our dataset is quite exhaustive as it includes images of different hand shapes and layout configurations. Using our dataset, we train a hand detector that is robust to background clutter and lighting variations. Our hand detector is implemented as a two-stage system. The first stage involves proposing hand hypotheses using complementary image features, which are then evaluated by the second stage classifier. This improves both precision and recall and results in a state-of-the-art hand detection method. In addition we develop a new method of non-maximum suppression based on super-pixels. We also contribute an efficient training algorithm for structured output ranking. In our algorithm, we reduce the time complexity of an expensive training component from quadratic to linear. This algorithm has a broad applicability and we use it for solving human layout estimation and taxonomic multiclass classification problems. For human layout, we use different body part detectors to propose part candidates. These candidates are then combined and scored using our ranking algorithm. By applying this bottom-up approach, we achieve accurate human layout estimation despite variations in viewpoint and layout configuration. In the multiclass classification problem, we define the misclassification error using a class taxonomy. The problem then reduces to a structured output ranking problem and we use our ranking method to optimise it. This allows inclusion of semantic knowledge about the classes and results in a more meaningful classification system. Lastly, we substantiate our ranking algorithm with theoretical proofs and derive the generalisation bounds for it. These bounds prove that the training error reduces to the lowest possible error asymptotically.