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Title: Plasma phytochemicals : mediators of CVD risk reduction and biomarkers of fruit and vegetable intake
Author: Jin, Yan Nan
ISNI:       0000 0004 2743 3869
Awarding Body: University of Reading
Current Institution: University of Reading
Date of Award: 2012
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This research is concerned with the analysis of data from two dietary intervention studies. The first study investigated the effects of acute ingestion of low-dose blackcurrant juice drink on the antioxidant capacity of plasma, acute measures of vascular reactivity and biomarkers of endothelial function: The second study was a randomized, controlled, dietary intervention study (FLAVURS) (n = 154) in which the test groups had sequential increases of 2,4 and 6 portions of high flavonoid or low flavonoid fruits and vegetables (F & V) every 6 weeks across an 18 week period. This thesis reports the dietary strategy to increase the amount and types of fruits and vegetables consumed by a free living population. Selected data from the study was used to develop an improved biomarker for F & V consumption, and data from the study was also used to investigate the association between plasma antioxidants and markers of vascular reactivity and endothelial function. The acute study showed that consumption of a 20% blackcurrant juice drink caused increases in plasma vitamin C (P=0.006), and urinary anthocyanins (P
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available