Quasi-free scattering reactions represent a direct way to learn about the properties of a nucleon inside the atomic nucleus. In such a nuclear reaction, a high energy particle knocks a bound nucleon directly out of a nucleus without any further violent interaction between the nucleus and the incident, or the nucleus and the two outgoing particles. Quasi-free scattering reactions are thus an ideal way to study the single-particle structure of nuclei and also how the nucleon-nucleon interaction is modified inside nuclear matter. With the availability of high-energy radioactive ion beams, it is now possible for the first time, to use quasi-free scattering reactions to study how such properties are modified inside isospin asymmetric nuclei and nuclear matter. In a recent pilot experiment at the GSI laboratory in Germany, proton induced quasi-free scattering was performed using the LAND/jR3B setup in Cave C. This kinematically complete setup is acting as a prototype for the future full R3B (Reactions with Relativistic Radioactive Beams) experiment and is based on an array of Si micro-strip detectors for tracking, and thick NaI scintillators for energy measurements. This allows for the detection of light recoil particles in coincidence with the detection of both charged particles, neutron and '"Y rays such that quasi-free reactions of the type (p,2p),(p,pn) and (p,pα) can be observed. The benchmark experiment was carried out using inverse kinematics with a 12C beam, at 400 A.Me V and since the structure of 12C is well known, and has been investigated with proton as well as electron knockout reactions, comparisons can be made with these measurements. This thesis will report on the results that have been achieved for the population of both bound and unbound states using the proton induced quasi-free reaction: 12C(p,2p)X as well as describing how the experimental setup is to be exten- ded for future experiments with higher energy radioactive ion beams at the FAIR facility