The intention of the work presented is to provide novel, accurate and time-efficient way of designing multi-sines stimulus signal to replace real-life modulated signals prevailing within telecommunication networks, hence providing a novel tool for the development of modern RF measurement and design solution. The work demonstrated that with 50 tones, the multi-sines stimulus excites almost the same level of nonlinearity as real modulated signals do. For this conclusion the investigation of nonlinear behaviour mechanism was taken and a real DUT was measured under designed multi-siness and various types of modulated signals. It is also demonstrated that this multi-sines stimulus is compatible with the advanced RF measurement systems which are capable of measuring the complete RF waveform including the harmonic and base-band frequencies but demanding a periodical stimulus signal. Furthermore, a novel and quick sub-sampling algorithm was proposed to efficiently use the memory of Sampling Oscilloscope and therefore allows for accurate multi-sines capturing. An averaging algorithm for multi-sines stimulus was proposed to “stabilize” the captured waveform and a PCA based phase compensating algorithm was also proposed to tackle the problem of frequency shift under multi-sines excitation.