Use this URL to cite or link to this record in EThOS:
Title: The effects of fruit and vegetable consumption on endothelial function and assessment of biomarkers for monitoring intake
Author: Alimbetov, Dauren Sembekovich
ISNI:       0000 0004 2717 6989
Awarding Body: University of Reading
Current Institution: University of Reading
Date of Award: 2011
Availability of Full Text:
Access from EThOS:
The literature reports that phytochemicals from fruits and vegetables, and fruit and vegetable- based products have been associated with decreased risk of cardiovascular disease (CVD). The current research has investigated the effects of fruits and vegetables and blackcurrant juice intake on endothelial function, vascular reactivity and biomarkers of consumption using two human interventions, one acute and one chronic. In addition, gene/nutrient interactions have been investigated with three genotypes linked to markers of CVD in the chronic study. / The acute study was a randomised, cross over, double blind, placebo controlled test meal study with 20 healthy volunteers (11 females 9 males). Subjects consumed a 20% blackcurrant juice drink or a control drink. Vascular reactivity was assessed at baseline and 120 mins after juice consumption by Laser Doppler Imaging (LDI). Acute consumption of 20% blackcurrant juice significantly increased plasma vitamin C (P=0.006), and urinary anthocyanins (P
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available