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Title: Small lingual carcinomas that metastasize may be predicted using morphological and immunohistochemical data
Author: Gibbins, Nicholas Edmund
ISNI:       0000 0004 2712 2091
Awarding Body: University of Brighton
Current Institution: University of Brighton
Date of Award: 2010
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Head and Neck squamous cell carcinoma is the 6th most common cancer in the first world and oral squamous cell carcinoma the 10th. It comprises 2-3% of all new malignancies diagnosed in the United Kingdom every year. Despite decades of research, the life expectancy of this disease remains the same as it was 30 years ago and its incidence has been rising over the last 10 years. 85% of lingual cancers are found on the tongue’s lateral border. It is known that these cancers spread early to regional lymph nodes. A metastatic cervical lymph node is the single most important factor in the prognosis of lingual cancer, with its presence indicating a 50% reduction in survival rates. Therefore finding predictive factors within these cancers that could foresee whether it will spread early would improve diagnosis, treatment and potentially survival.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: A000 Medicine