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Title: Quantitative studies of high intensity focused ultrasound induced biological damage
Author: Rivens, Ian
Awarding Body: Institute of Cancer Research (University Of London)
Current Institution: Institute of Cancer Research
Date of Award: 1992
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The objective of this project is to contribute to the development of therapeutic ultrasound as a surgical technique for the "non-invasive" treatment of discrete liver tumours. The design, focusing and calibration of high intensity sound sources is discussed, and equipment used to treat specimens ranging in weight from a few grams up to several hundred kilograms, is described. The dependence of damage (lesion) dimensions in excised liver samples (at an ambient temperature of 37°C) on the ultrasonic free-field spatial peak intensity (between 1350 and 5400 Wcm⁻²) and the depth of the focal plane beneath the tissue surface (between 10 and 30 mm) was investigated over a range of exposure times (1
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Phd
EThOS ID:  DOI: Not available