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Title: Ocular thermography in health and disease
Author: Morgan, P. B.
ISNI:       0000 0001 2410 1189
Awarding Body: The University of Manchester
Current Institution: University of Manchester
Date of Award: 1994
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There has been interest in ocular temperature for over a century, with the publication of a limited amount of literature over that time. This thesis reports on the development and utilisation of a system for the measurement of ocular surface temperature based on an advanced infrared detector. The development of a suitable protocol for the infrared imaging and temperature measurement of the eye was established. Results from the analysis of the ocular temperature of 98 normal subjects indicated that the temperature at the centre of the cornea was 31.68 ± 0.60°C (mean ± SD), and the mean ocular surface temperature (MOST) was 32.10 ± 0.53°C. This value rose with increasing room and oral temperature (both p< 0.0001) and decreased with corneal thickness (p< 0.05) and age (p< 0.01). Ninety five per cent of the subjects had an inter-ocular difference in MOST within 0.53°C. There was a positive relationship between the variation in temperature across the ocular surface and the distance between the corneal apex and a coronal plane through the limbus (p< 0.001). The effect on eye temperature of changes in the ocular blood, nerve and tear supplies was studied. Three of nine patients (33%) with unilateral inflammatory disease had ocular temperature outside the established normal limits. For the group of patients as a whole, the temperature of the affected eye was warmer than the fellow (32.40 ± 0.81°C compared with 32.10 ± 0.70°C; p< 0.05). In a further study, there was a significant negative relationship between the degree of stenosis of the carotid artery and eye temperature (p< 0.001). In the examination of two patients with Horner's syndrome, one demonstrated a difference in eye temperature (0.61°C) outside normal limits (0.53°C), with the affected eye being warmer.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available