| Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506243 |
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| Title: | Electrophysiological and molecular studies of SCN5A mutations related to sick sinus syndrome | ||||
| Author: | Gui, Junhong |
ISNI:
0000 0004 2676 5992
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| Awarding Body: | The University of Manchester | ||||
| Current Institution: | University of Manchester | ||||
| Date of Award: | 2009 | ||||
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| Abstract: | |||||
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SCN5A is the gene encoding the a subunit of the cardiac voltage-gated sodium channel, hNav1.5. The ionic current through this channel, which is responsible for the upstroke of the cardiac action potential, plays an important role in normal cardiac rhythm in the heart. Genetic defects of SCN5A have been linked with several cardiac arrhythmic disorders including sick sinus syndrome (SSS).
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| Supervisor: | Not available | Sponsor: | Not available | ||
| Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||
| EThOS ID: | uk.bl.ethos.506243 | DOI: | Not available | ||
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