| Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505784 |
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| Title: | Beneficial effects of statins on the microcirculation during sepsis | ||||
| Author: | McGown, Caroline Christina | ||||
| Awarding Body: | The University of Sheffield | ||||
| Current Institution: | University of Sheffield | ||||
| Date of Award: | 2009 | ||||
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| Abstract: | |||||
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Background: Sepsis may be modelled in vivo using lipopolysaccharide (LPS) to cause microvascular disturbances including macromolecular leak and leucocyte adhesion. Such changes may be due to an altered balance of eNOS and iNOS. Statins are widely used to lower cholesterol. Recently evidence indicates statins may exert pleiotropic effects, possibly restoring physiological levels of eNOS and iNOS.
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| Supervisor: | Not available | Sponsor: | Not available | ||
| Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||
| EThOS ID: | uk.bl.ethos.505784 | DOI: | Not available | ||
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