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Title: Site-directed integration of tissue-specific transgenes in the malaria vector mosquito Anopheles gambiae
Author: Basu, Sanjay
ISNI:       0000 0004 2678 6953
Awarding Body: Keele University
Current Institution: Keele University
Date of Award: 2009
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Malaria is the most prolific worldwide parasitic infection and is caused by a protozoan infection transmitted by Anopheles mosquitoes. The deadliest form of the disease is caused by Plasmodium falciparum for which the major vector in the endemic region of sub-Saharan Africa is Anopheles gambioe. Alongside vaccine research and drug development there are more novel approaches such as theoretical population replacement strategies employing transgenic mosquitoes. A key component in this strategy is the generation of mosquitoes carrying a transgene that can disrupt the parasite lifecycle and prevent transmission when that insect takes a bloodmeal.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available