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Title: Developing a macrocyclic sensor to probe interactions in biology
Author: White, Rebecca
ISNI:       0000 0004 2674 805X
Awarding Body: University of Leeds
Current Institution: University of Leeds
Date of Award: 2009
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This thesis describes the development of a small molecule sensor for the detection of specific protein-protein interactions. The responsive sensor has been designed to produce a measurable signal upon a bivalent interaction with a dimeric protein target, and has the potential to probe the biological significance of specific binding events.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Drug discovery process