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Title: Psychophysical properties and neural correlates of superficial and deep tissue pain
Author: Cameron, Heather
ISNI:       0000 0004 2672 5659
Awarding Body: University of Liverpool
Current Institution: University of Liverpool
Date of Award: 2008
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The projects described in this thesis 'investigate the psychophysical properties and .neural correlates of cutaneous and muscle pain in healthy volunteers and in a small patient group. A total of four experiments are reported; two in healthy volunteers and two in patients with lateral epicondylitis The first experiment investigated psychophysical differences between intradermal, subcutaneous and intramuscular pain induced by hypertonic saline injections. The pain descriptors used by the subjects were d~fferent between the three injections. The profile of pain, including the intensity and time course and response to each single injection, was similar between intradermal and intramuscular injections whereas results were inconsistent with subcutaneous injections. The second study, employing the methods developed in the first, used functional magnetic resonance imaging (fMRI) of the brain to undertake a comparison of the neural activation patterns associated with intradermal and intramuscular pain.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral