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Title: Use of pulsed electric fields in transformation of potential expression systems for biopharmaceuticals
Author: Avulamanda, Chandan
ISNI:       0000 0004 2671 0932
Awarding Body: The University of Strathclyde
Current Institution: University of Strathclyde
Date of Award: 2008
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The use of short high voltage pulses to overcome the barrier of the cell membrane by creating pores is known as electroporation. Pulsed electric fields can cause irreversible and reversible breakdown of the cell membrane thereby this technology can be applicable for sterilization processes as well as to enhance the transportation rate of foreign particles across the membrane. Transformation efficiency still remains the challenging aspect of the process. Due to the limitations of the pulse generators; available, the past research on electroporation has been limited to small treatment volumes with limited flexibility to optimise the process parameters.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available