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Title: The development of a reporter system for Bacillus cereus to establish the environmental conditions needed for production of Bacillus cereus enterotoxin T (bceT)
Author: Laird, Brian
ISNI:       0000 0004 2671 0211
Awarding Body: The University of Strathclyde
Current Institution: University of Strathclyde
Date of Award: 2009
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Bacillus cereus is primarily a soil-dwelling bacterium, however it is also pathogenic bacterium, which is implicated in many food poisoning outbreaks throughout the world. It is responsible for both non-gastrointestinal and gastrointestinal infection with the former leading to many working days lost. Two types of infection exist, the emetic Infection and the diarrhoeal infection. The emetic infection is caused by a heat stable protein, which causes vomiting and stomach cramps. The diarrhoeal infection is caused by several different toxins including haemolysin BL (HBL), non-haemolytic enterotoxin (NHE), B. cereus enterotoxin T (bceT), cytotoxin K (cytK), the recently discovered Hlyll toxin and enterotoxin Fm (entFM). The purpose of this project was to develop a reporter system that could be used to investigate the environmental conditions necessary for the production of Bacillus cereus enterotoxin T (bceT) after human ingestion. A plasmid was constructed that carried the bceT gene, which would ultimately be integrated Into the B. cereus chromosome after manipulation.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available