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Title: Computational classification of small RNAs and their targets
Author: Moxon, Simon
ISNI:       0000 0004 2669 1559
Awarding Body: University of East Anglia
Current Institution: University of East Anglia
Date of Award: 2008
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Small RNAs, and in particular microRNAs, are currently receiving a great deal of attention due to their important roles in gene regulation and organism development. Recently, new high-throughput technologies have made it possible to sequence hundreds of thousands of small RNAs from a single experimental sample. In this thesis we develop new computational tools to process such high-throughput small RNA datasets in order to identify microRNAs and other biologically interesting small RNA candidates and to predict their target genes. We apply these tools to a variety of plant and animal datasets and present some novel discoveries including miRNAs involved in fruit development in tomato (Solanum lycopersicon).
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available