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Title: Novel contributions to understanding the mechanism of folate transport and anti-folate resistance in Plasmodium falciparum
Author: Ochong, Edwin Omondi
ISNI:       0000 0004 2674 0314
Awarding Body: University of Liverpool
Current Institution: University of Liverpool
Date of Award: 2008
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The primary focus of the PhD thesis has exclusively been on studies on Plasmodium falciparum with a remit to build a clear understanding on some of the critical and relevant questions relating to folates transport and antifolates resistance. The direction of this work has been constructed on the following themes of interest; 1. The Influence of folate pathway substrates on the In Vitro activities of antifolate drugs. 2. Functional characterization of heterologously expressed putative folate transporters in the Xenopus laevis oocyte. 3. Transcriptional analysis of putative folate transporter genes.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available