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Title: A novel electrochemical lateral flow immunoassay
Author: Gray, Louise Elizabeth
ISNI:       0000 0004 2673 8169
Awarding Body: The University of Strathclyde
Current Institution: University of Strathclyde
Date of Award: 2008
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Cardiac surgery with cardiopulmonary bypass (CPB) can trigger systemic inflammatory response syndrome (SIRS) in patients. Pro-inflammatory cytokines lL-6 and IL-8 are reported as particular markers in blood of the inflammatory •espouse to CPB. It would be useful to measure the inflammatory response in the surgical theatre in real/near real time to improve the effectiveness and timings for interventions which may counteract any undesirable inflammatory response. Currently, Enzyme Linked Immunosorbent Assays (ELISAs) and similar systems are used in the central laboratory to measure inflammatory markers however they do not provide results within the appropriate timescale for rapid intervention. Consequently other approaches to assay provision at point of care must be considered. This thesis is concerned with the design, fabrication and characterisation of a prototype, electrochemical, lateral flow system opening a new approach to rapid, point of care (POC), quantitative monitoring of inflammatory markers.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available