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Title: Humanised recombinant antibodies for human cancer therapy
Author: Davidson, Lisa
ISNI:       0000 0004 2673 6788
Awarding Body: The University of Strathclyde
Current Institution: University of Strathclyde
Date of Award: 2009
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Humanisation of rodent mAbs by CDR-grafting is now a standard procedure for reducing immunogenicity and recruiting human effector functions with ten humanised mAbs approved for use and many more in development. This project aimed to develop two anti-cancer therapeutics aimed at exploiting two tumour associated antigens overexpressed in the tumour environment.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available