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Title: Analysis of nanoparticulate coatings with relevance to dentine sensitivity
Author: Convery, Joanne Marie
ISNI:       0000 0004 2673 1338
Awarding Body: University of Liverpool
Current Institution: University of Liverpool
Date of Award: 2008
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Dentine sensitivity is a common dental complaint. It is caused by the exposure of root dentine to the oral environment. A popular method of overcoming dentine sensitivity is the occlusion of the dentinal tubules. In this thesis the use of nanoparticulate silica sols, of sizes 7, 14 and 21 nm diameter for the treatment of dentine sensitivity, as occluding agents was explored. Previous work at the University of Liverpool has identified a simple two step method for coating surfaces in silica nanoparticles. This process required the use of a poly cationic polymer (Zetag 7689). TEM and QCM-D were used to observe the creation of nanoparticulate coatings, in the absence and following manipulation of the polymer binding layer. It was demonstrated that on gold, carbon and hydroxyapatite surfaces a polymer binding layer was required. However, using the QCM-D and XPS it was identified that on dentine surfaces a polymer binding layer was unnecessary.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral