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Title: Characterisation of malathion resistance mechanisms and stress responses of susceptible and resistant strains of red flour beetle Tribolium castaneum (Herbst)
Author: Rauf, Abdur
ISNI:       0000 0004 2670 5981
Awarding Body: University of Newcastle Upon Tyne
Current Institution: University of Newcastle upon Tyne
Date of Award: 2009
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The extensive use of insecticides to control insect pests has provided a dramatic illustration of evolution in natural populations. Malathion resistance in the red flour beetle, Tribolium castaneum (Herbst), is a worldwide problem and is very stable once it becomes widespread in natural populations. It is not surprising that resistant and susceptible 5 strains differ in properties other than their adaptation to insecticides, such as development time, fecundity and fertility. The present study investigated the biochemical mechanisms of resistance in a highly malathion specific resistant strain of T. castaneum (PH-1) which was kept under repeated selection pressure resulting in a very high level of resistance as compared to the susceptible strain, and its fitness against oxidative and pathogenic stresses. General esterase, malathion-specific carboxylesterase, glutathione S-transferase and target site sensitivity were compared, in this and a susceptible strain, to better understand biochemical mechanisms of resistance.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available