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Title: Age-related changes in osteoarthritic chondrocytes
Author: Scott, Jenny Louise
ISNI:       0000 0004 2670 2000
Awarding Body: University of Newcastle Upon Tyne
Current Institution: University of Newcastle upon Tyne
Date of Award: 2009
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Age is the most important risk factor in the development of osteoarthritis (OA). Numerous studies have now demonstrated that age-related changes occur in both the extracellular matrix and chondrocytes of OA cartilage and such changes are proposed to alter the tissue's biomechanical properties, thus predisposing to OA onset. The study presented here describes further investigation of two such age-related changes, cellular senescence and oxidative stress.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available