Neuronal oscillations have been implicated in various cognitive functions in vivo and can be correlated to a variety of behavioural states. Hippocampal gamma (20-80 Hz) and theta (4-15 Hz) frequency neuronal oscillations have been reported to play a role in memory and representation of visuospatial information. Noradrenaline, a neurotransmitter released during arousal, is an important factor in information acquisition and ma}g of novel spatial information. The aim of this thesis was to investigate the cellular mechanisms by which noradrenaline modulates hippocampal gamma and theta frequency oscillations in the hippocampus in vitro.