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Title: The neuroplastin cell adhesion molecules : activation of signalling pathways and characterization of the homophilic binding mechanism
Author: Bates, Katharine Jane
ISNI:       0000 0004 2670 0697
Awarding Body: Royal Holloway, University of London
Current Institution: Royal Holloway, University of London
Date of Award: 2008
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The neuroplastins np65 and np55 are synapse-enriched members of the immunoglobulin superfamily of cell adhesion molecules. The neuroplastins contain two extracellular immunoglobulin-like domains, a single transmembrane domain followed by a short intracellular domain. Np65 differs from np55 by the presence of a third N-termmal Ig domain. They arise by alternative splicing of the same gene transcript. Np65, but not np55 exhibits homophilic binding.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available