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Title: X-ray and neutron macromolecular crystallography : new methodologies and structural studies on DNA oligonucleotides
Author: Leal, Ricardo Miguel Ferraz
ISNI:       0000 0004 2672 9932
Awarding Body: Keele University
Current Institution: Keele University
Date of Award: 2009
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This PhD project had two parts. The first part concerned the development of a number of specific instrumentation and software approach of general use for X-ray and neutron crystallography. Central to this was a proof of principle study in which novel 3D computational methods were developed to allow an accurate model to be built of cryo-frozen crystals and supporting loop and liquid. It is demonstrated that this type of approach may be used to optimise crystallographic absorption corrections that offer particular advantages for situations where data redundancy is low.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available