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Title: Modulation of the transient outward K+ channel, Kv1.4, by extracellular acidosis, extracellular K+ and polyunsaturated fatty acids
Author: Farag, Noha Elsayed Hassan
ISNI:       0000 0004 2669 7547
Awarding Body: University of Manchester
Current Institution: University of Manchester
Date of Award: 2009
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During metabolic inhibition caused by myocardial ischemia, the extracellular pH reduces, while the concentrations of extracellular K+ and free polyunsaturated fatty acids (PUFAs) increase. Acidosis, raised extracellular K+ and PUFAs nodulate the rapidly inactivating K+ channel, Kv1.4, that contributes to the transient outward K+ current (1to) in the heart, including in the human.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available