| Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498814 |
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| Title: | Modulation of the transient outward K+ channel, Kv1.4, by extracellular acidosis, extracellular K+ and polyunsaturated fatty acids | ||||
| Author: | Farag, Noha Elsayed Hassan |
ISNI:
0000 0004 2669 7547
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| Awarding Body: | University of Manchester | ||||
| Current Institution: | University of Manchester | ||||
| Date of Award: | 2009 | ||||
| Availability of Full Text: |
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| Abstract: | |||||
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During metabolic inhibition caused by myocardial ischemia, the extracellular pH reduces, while the concentrations of extracellular K+ and free polyunsaturated fatty acids (PUFAs) increase. Acidosis, raised extracellular K+ and PUFAs nodulate the rapidly inactivating K+ channel, Kv1.4, that contributes to the transient outward K+ current (1to) in the heart, including in the human.
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| Supervisor: | Not available | Sponsor: | Not available | ||
| Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||
| EThOS ID: | uk.bl.ethos.498814 | DOI: | Not available | ||
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