Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498813 |
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Title: | Optimal designs for cost-efficient assessment of exposure subject to measurement error | ||||||
Author: | Batistatou, Evridiki |
ISNI:
0000 0004 2669 7520
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Awarding Body: | University of Manchester | ||||||
Current Institution: | University of Manchester | ||||||
Date of Award: | 2009 | ||||||
Availability of Full Text: |
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Abstract: | |||||||
In epidemiological studies of an exposure-response association, often only a mismeasured exposure is taken on each individual of the population under study. If ignored, exposure measurement error can bias the estimated exposure-response association in question. A reliability study may be carried out to estimate the relation between the mismeasured and true exposure, which could then be used to adjust for measurement error in the attenuated exposure-response relationship. However, taking repeated exposure measurements may be expensive. Given a fixed total study cost, a two-stage design may be a more efficient approach for regression parameter estimation compared to the traditional single-stage design since, in the second-stage, repeated measurement is restricted to a sample of first-stage subjects. Sampling the extremes of the first-stage exposure distribution has been shown to be more efficient than random sampling.
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Supervisor: | McNamee, R. | Sponsor: | Not available | ||||
Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||||
EThOS ID: | uk.bl.ethos.498813 | DOI: | Not available | ||||
Keywords: | Exposure measurement error, bias-correction | ||||||
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