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Title: Characterisation of seven transmembrane helical protein primary structure and interactions by mass spectrometry
Author: Freeman, Hamzah Neil Martin
ISNI:       0000 0004 2673 2250
Awarding Body: Birkbeck (University of London)
Current Institution: Birkbeck (University of London)
Date of Award: 2008
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Summary: The solubilisation and enrichment of protein complexes with affinity resins was investigated using a tagged-human adenosine A1a receptor expressed in CHO cells. A range of known and potential binding partners were identified by peptide mass spectrometry in both agonist and antagonist treated membrane extracts, that showed striking similarity to protein partners identified in published studies on other G protein-coupled receptors.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available