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Title: An investigation into mechanisms underlying neutrophil-mediated oedema in vivo
Author: Al-Kashi, Adam
ISNI:       0000 0001 3406 5425
Awarding Body: Imperial College London
Current Institution: Imperial College London
Date of Award: 2008
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Neutrophils play a crucial role in the acute immune response. Inflammatory stimuli recruit neutrophils into the tissues. Post-migratory neutrophils may then engage in pathogen killing and phagocytosis. Oedema-formation is associated with neutrophil transmigration, although evidence indicates that these are mechanistically distinct phenomena. Leukocyte-driven oedema is a feature of many inflammatory diseases including asthma, rheumatoid arthritis, and Crohn's disease, the mechanisms underlying neutrophil-mediated oedema are unclear.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available