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Title: Understanding the in vivo role of Rac1 in angiogenesis
Author: D'Amico Lago, Gabriela Veronica
ISNI:       0000 0004 2670 6271
Awarding Body: Queen Mary, University of London
Current Institution: Queen Mary, University of London
Date of Award: 2008
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In this Thesis, I describe my studies on understanding the in vivo role of Rac1 in angiogenesis. Angiogenesis, the formation of new blood vessel from pre-existing ones, is required during embryogenesis and in a variety of pathological conditions, including cancer. Rac1, a member of the Rho family of small GTPases, has been implicated in integrin and growth factor signal transduction and is thought to regulate cell migration and proliferation; both vital processes-in angiogenesis. However the precise role of Rac1 in angiogenesis in vivo is unknown.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available