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Title: Airway remodelling and transforming growth factor (TGF)-β superfamily signalling in allergen-induced asthma
Author: Kariyawasam, Harsha Hemantha
ISNI:       0000 0004 2670 3089
Awarding Body: Imperial College London (University of London)
Current Institution: Imperial College London
Date of Award: 2007
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Bronchial biopsies obtained at baseline, 24 hours and 7 days after allergen challenge from mild atopic asthmatics were evaluated to follow the initiation and resolution of allergen-induced inflammation and remodelling in relation to AHR. Further, the expression patterns of the TGF-β Superfamily ligands (TGF-β₁₋₃, activin-A, BMP-2, BMP-4 and BMP-7) and their respective signalling pathway Type II receptors, Type I receptors and signalling Smad proteins were defined in baseline asthma and after allergen provocation in comparision with normal volunteers.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available