| Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497870 |
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| Title: | Airway remodelling and transforming growth factor (TGF)-β superfamily signalling in allergen-induced asthma | ||||||
| Author: | Kariyawasam, Harsha Hemantha |
ISNI:
0000 0004 2670 3089
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| Awarding Body: | Imperial College London (University of London) | ||||||
| Current Institution: | Imperial College London | ||||||
| Date of Award: | 2007 | ||||||
| Availability of Full Text: |
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| Abstract: | |||||||
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Bronchial biopsies obtained at baseline, 24 hours and 7 days after allergen challenge from mild atopic asthmatics were evaluated to follow the initiation and resolution of allergen-induced inflammation and remodelling in relation to AHR. Further, the expression patterns of the TGF-β Superfamily ligands (TGF-β₁₋₃, activin-A, BMP-2, BMP-4 and BMP-7) and their respective signalling pathway Type II receptors, Type I receptors and signalling Smad proteins were defined in baseline asthma and after allergen provocation in comparision with normal volunteers.
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| Supervisor: | Not available | Sponsor: | Not available | ||||
| Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||||
| EThOS ID: | uk.bl.ethos.497870 | DOI: | Not available | ||||
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