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Title: A self-consistent approach to the simulation of ionic motion in open ion channels
Author: Tindjong, Rodrigue
ISNI:       0000 0004 2673 8249
Current Institution: Lancaster University
Date of Award: 2006
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In this thesis, we develop the theoretical and numerical foundations for a self-consistent model for the simulation of the properties of ion channels - their conductivity and selectivity - from their structure. We begin by revising the one-dimensional theory of the ionic current by setting up the self-consistent coupled Langevin Poisson equations in one-dimension, as a prototype of the three dimensional simulations. The solution of a one-dimensional approximation of the Poisson's equation for a channel modelled as a long and narrow cylindrical tube is derived. Using this solution, we calculate the ion trajectory as it traverses the channel.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available