Use this URL to cite or link to this record in EThOS:
Title: Investigation of SUMO phosphorylation and analysis of selected targets of the two sumo ligases NSE2 and PLI1
Author: Skilton, Andrew Michael
ISNI:       0000 0004 2670 9915
Current Institution: University of Sussex
Date of Award: 2009
Availability of Full Text:
Access from EThOS:
SUMO (Small Ubiquitin-like Modifier) is a post-translational modifier, which is conjugated to its targets through a pathway analogous to that of ubiquitinylation. SUMO is implicated in a variety of cellular processes that have consequences for the repair of DNA damage and cell cycle progression. This is reflected in the fact that S. pombe cells, mutant for the SUMO conjugation pathway, are sensitive to genotoxins and have aberrant cellular morphologies and defects in DNA segregation.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available