Use this URL to cite or link to this record in EThOS:
Title: Dearomatising cyclisations onto pyridines
Author: Brice, Heloise
ISNI:       0000 0004 2675 1507
Awarding Body: University of Manchester
Current Institution: University of Manchester
Date of Award: 2009
Availability of Full Text:
Full text unavailable from EThOS.
Please contact the current institution’s library for further details.
This thesis details investigations into the dearomatising cyclisation onto pyridines. Studies into the cyclisation of enolate or silyl enol ether nucleophiles onto a pyridine ring are described. Flexible hydrocarbon tethers and tethers incorporating either an oxygen or nitrogen atom were investigated and novel fused 6.5 and 6.6 bicyclic piperidines have been synthesised. A one-pot silyl enol ether or silyl ketene acetal formation and cyclisation procedure has been developed.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available