Use this URL to cite or link to this record in EThOS:
Title: Investigation on the role of lipids in the regulation of protein function
Author: Tsaloglou, Maria-Nefeli
ISNI:       0000 0004 2674 1800
Awarding Body: University of Southampton
Current Institution: University of Southampton
Date of Award: 2008
Availability of Full Text:
Access from EThOS:
Access from Institution:
Type 11 amphiphiles have been shown in vitro to activate the catalytic activity of ate-determining enzyme of lipid metabolism CTP: phosphocholine cytidylyltransferase (CCT). Membrane stored curvature elastic stress has been suggested as a regulator of CCT activity. It has been postulated that Type II lipids, which form membranes with high curvature elastic stress, activate CCT by increasing the partitioning of CCT onto the membrane. Conversely, Type I lipids inhibit CCT activity by decreaskig stored elastic energy.
Supervisor: Attard, George Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: QD Chemistry