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Title: Regulation of viral gene expression during infection with enteric viruses
Author: Katafigiotis, Sokratis
ISNI:       0000 0004 2670 0670
Current Institution: University of Nottingham
Date of Award: 2008
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In this study two enteric viruses, poliovirus and adenovirus type 40, were used to investigate virus - host cell interactions in the gastrointestinal environment. Human enteric adenoviruses have been previously shown to be sensitive to IFN-treatment of cells and a STAT-deficient cell line allows improved growth of enteric adenovirus type 40. Two adenoviral gene products, the virus-associated RNA (VA RNA) and the El A, have been previously shown to be responsible for viral countermeasures against IFN actions in the host cell.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available