'Previous studies (Brat, et al, 2006) have shown that the consumption of fruit and vegetables play a role in preventing the onset ot cardiovascular diseases, such as itherosclerosis, ischemic heart disease and coronary heart disease. These beneficial effects on cardiovascular health have been suggested to be due to the presence of polyphenolic compounds and perhaps their antioxidant capacity. The aim ot the study was to investigate whether dietary polyphenols have any direct ettects on vascular endothehal cell expression of genes involved in angiogenesis and other roles of the endothelium and whether physiological concentrations of the red wine polyphenols Quercetin and Resveratrol have a beneficial effect on vasoconstriction and vasodilation at the gene expression and protein expression level.