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Title: The diversity of HIV-1
Author: Archer, John Patrick
ISNI:       0000 0004 2668 5191
Current Institution: University of Manchester
Date of Award: 2008
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The phylogeny of the Human Immunodeficiency Virus type 1 (HIV-1) is characterized by extensive diversity. However when it comes to the persistence of the virus not all of this diversity is relevant. In this thesis I show that the significance of diversity, both In relation to epidemiology and vaccine design, varies within and between the HIV-1 groups. The substructure present within group O and at the center of the group M pandemic was observed to be similar to that found on random tree topologies, whereas the substructure present within globally sampled group M strains was significantly different.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available