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Title: Non-myeloablative allotransplantation combined with tumour-specific vaccination for the treatment of prostate cancer
Author: Michelini, Rodrigo Hess
ISNI:       0000 0001 3397 4352
Awarding Body: Open University
Current Institution: Open University
Date of Award: 2008
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Mechanisms of tolerance induced by tumour cells hamper natural and vaccine-induced protective immune responses in cancer patients. Thus, strategies to overcome tolerance and restablish anti-tumour immunity have been attempted. Non-myeloablative haematopoietic cell transplantation can cure patients affected by haematological malignancies but has had limited success against solid tumours. This is possibly because of peripheral tolerance induction and/or suboptimal priming of tumour-specific T lymphocytes.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available