Sustainable industrial activity requires that processes should use raw materials as efficiently as is economic and practical to preserve the resources as much as possible. The major source of inefficiency in the use of raw material in most chemical processes is in chemical reactors. This work focuses on developing various design options that allow the raw materials efficiency of chemical reactors to be improved by the simultaneous design of the catalyst and the reactor. Practical consideration such as the deterioration of performance of the catalytic reactor or network of catalytic reactors through time, resulting from catalyst deactivation is considered in this work to make reactor designs more reliable and practical.