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Title: In silico investigation of amyloid
Author: Clarke, Oliver James
ISNI:       0000 0001 3558 2221
Awarding Body: University of Leeds
Current Institution: University of Leeds
Date of Award: 2008
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Amyloid fibrils, highly ordered aggregates of mis-folded protein with a characteristic cross-beta structure, are associated with several diseases including Alzheimer's disease and the prion diseases. Amyloid fibrils are difficult to study experimentally and there is litde high resolution structural data available; therefore simulation methods have an important role to play in characterising the structures of these early species and the forces holding them together.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available