Osteoporotic fractures in the elderly are a worldwide epidemic and the increasing ageing of the global population means that the economic cost of these fractures will continue to rise. Leading a physically active lifestyle offers one preventative measure, so it is important that the general public knows precisely how to exercise. This thesis describes investigations into the effects of brief, high-impact, unilateral exercise on neuromuscular and bone health, concentrating on defining the optimum weekly frequency of exercise required for healthy but sedentary premenopausal women to maximise their peak bone mass.