Use this URL to cite or link to this record in EThOS:
Title: The role of DNMT1 inhibition in the identification of epigenetically silenced genes in pituitary tumours
Author: Dudley, Kevin
ISNI:       0000 0001 3433 8315
Awarding Body: Keele University
Current Institution: Keele University
Date of Award: 2009
Availability of Full Text:
Access from EThOS:
Epigenetic unmasking, either by pharmacological inhibition or direct gene targeting, has been utilised to identify novel tumour suppressor genes that are silenced in association with inappropriate CpG island (CGI) methylation in various types of cancer. In this study, an epigenetic unmasking strategy was developed to identify novel genes that are silenced in association with inappropriate, CGI methylation in pituitary tumours.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available