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Title: Development of new photosensitising drugs for antibacterial therapy
Author: O'Grady, Cassandra Clare
ISNI:       0000 0001 3452 8960
Awarding Body: University of Leeds
Current Institution: University of Leeds
Date of Award: 2003
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Antimicrobial photodynamic therapy (APDT) is a novel treatment method for the destruction of microorganisms. APDT uses the combined effect of a photosensitising drug, light and molecular oxygen to bring about a toxic effect. The work presented in this study investigates the photodynamic antibacterial efficacy of a series of symmetrical cationic phenothiazinium salts. The photosensitisers investigated were lipophilic derivatives of methylene blue, where the methyl groups of methylene blue are replaced with longer alkyl chains from ethyl to n-hexyl.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available