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Title: Expression, purification characterisation of the extracellular N-terminal domain of human neuronal a nicotinic acetylcholine receptor of E coli and insect cells
Author: Ferrandon, Sebastien
ISNI:       0000 0001 3461 8747
Awarding Body: Oxford Brookes University
Current Institution: Oxford Brookes University
Date of Award: 2005
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This thesis was aimed at the over-expression of the extracellular N-terminal domain (ECD) of the human α7 nicotinic acetylcholine receptor (nAChR). The ECD of the α7 nAChR is more suitable than the ECD of other nAChR subunits for crystallographic studies, mainly because the receptor is oligomeric and does not require any other nAChR subunit ECD to form a complete agonist/antagonist binding domain.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available