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Title: Type II DNA topoisomerases in zebrafish development
Author: Azrak, Sami
ISNI:       0000 0001 3434 5734
Awarding Body: Newcastle University
Current Institution: University of Newcastle upon Tyne
Date of Award: 2008
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DNA topoisomerases are vital enzymes for major cellular processes like replication, transcription, and chromosome segregation. They play an essential role in solving DNA topological problems by catalysing the passage of DNA strands through each other via introducing transient single or double strand breaks. Type IIA DNA topoisomerases members introduce double strand breaks via an ATP-dependent strand passage reaction. This study aimed to investigate the roles of topo Ila and topo Iip in zebrafish development.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available