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Title: Study of metallothionein-1 mRNA and its interaction with elongation factor 1 alpha
Author: Fan, Kunbo
ISNI:       0000 0001 3456 7847
Awarding Body: Newcastle University
Current Institution: University of Newcastle upon Tyne
Date of Award: 2008
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Metallothioneins (MT) are small metal-binding proteins. Metallothionein isoform MT-1 alters localization from cytoplasm to nucleus as cells enter S phase. The perinuclear localization of MT-1 mRNA is essential for this nuclear localization. The localization of the MT-1 mRNA requires a signal in the 3'untranslated region (3'UTR). This thesis describes studies of the localization signal in the MT-1 3'UTR and its binding to transacting cellular proteins.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Bioactive proteins