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Title: Regulation of intratubular T cell adhesion by chemokines in renal allograft rejection
Author: Al-Hamidi, Abdulaziz H.
ISNI:       0000 0001 3405 9340
Awarding Body: Newcastle University
Current Institution: University of Newcastle upon Tyne
Date of Award: 2008
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Cell-mediated renal allograft rejection is defined by infiltration of the tubules by activated T cells which can express the aE(CD103)B7 integrin. Whilst this molecule may allow adhesion to E-cadherin expressed by tubular epithelial cells, the potential of intratubular chemokines to activate this adhesive process has not been investigated. Initial studies showed that intratubular T cells can express the chemokine receptor CCR9.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available